Publikationsliste

2015

31 Dec 2015; ().

Combined CXCR3/CXCR4 measurements are of high prognostic value in chronic lymphocytic leukemia due to negative cooperativity of the receptors

Ganghammer S, Gutjahr J, Hutterer E, Krenn PW, Pucher S, Zelle-Rieser C, Jöhrer K, Wijtmans M, Leurs R, Smit MJ, Gattei V, Greil R, Hartmann TN

Haematologica 20 Nov 2015; (). [Epub ahead of print]

Bone marrow microenvironmental CD4 + and CD8 + lymphocyte infiltration patterns define overall- and progression free survival in standard risk multiple myeloma - an analysis from the Austrian Myeloma Registry

Willenbacher W, Willenbacher E, Zelle-Rieser C, Biedermann R, Weger R, Jöhrer K, Brunner A

Leuk Lymphoma 16 Nov 2015; (). [Epub ahead of print]

Treg(s) in Cancer: Friends or Foe?

Wolf D, Sopper S, Pircher A, Gastl G, Wolf AM

J Cell Physiol 1 Nov 2015; 230(11)2598-605.

Optimized stem cell detection using DyeCycle-triggered side population phenotype

M. Bösch, D. Wolf, S. Sopper

Stem Cell Int 1 Oct 2015; (). [in press]

Noncytolytic CD8+-mediated antiviral response represents a strong element in the immune response of simian immunodeficiency virus-infected long-term non-progressing rhesus macaques

A. Javed, N. Leuchte, B. Neumann, S. Sopper, U. Sauermann

PlosOne 1 Oct 2015; ().

The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance

Hermann-Kleiter N, Klepsch V, Wallner S, Siegmund K, Klepsch S, Tuzlak S, Villunger A, Kaminski S, Pfeifhofer-Obermair C, Gruber T, Wolf D, Baier G

Cell Rep 29 Sep 2015; 12(12)2072-85.

Activators and stimulators of soluble guanylate cyclase counteract myofibroblast differentiation of prostatic and dermal stromal cells

Zenzmaier C, Kern J, Heitz M, Plas E, Zwerschke W, Mattesich M, Sandner P, Berger P

Exp Cell Res 26 Sep 2015; (). [Epub ahead of print]

Liver Transplantation-Associated Lung Cancer: Comparison of Clinical Parameters and Outcomes

Kocher F, Finkenstedt A, Fiegl M, Graziadei I, Gamerith G, Oberaigner W, Vogel W, Hilbe W

Clin Lung Cancer 16 Sep 2015; 16(5). Epub 2015 Feb 17.

OMIP-026: Phenotypic analysis of B and plasma cells in rhesus macaques

Neumann B, Sopper S, Stahl-Hennig C

Cytometry A 1 Sep 2015; 87(9)800-2.

Drug Transporter-Mediated Protection of Cancer Stem Cells From Ionophore Antibiotics

Boesch M, Zeimet AG, Rumpold H, Gastl G, Sopper S, Wolf D

Stem Cells Transl Med 1 Sep 2015; 4(9)1028-32.

Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re-sensitization by JNK inhibition

Nicholson L, Evans CA, Matheson E, Minto L, Keilty C, Sanichar M, Case M, Schwab C, Williamson D, Rainer J, Harrison CJ, Kofler R, Hall AG, Redfern CP, Whetton AD, Irving JA

Br J Haematol 27 Aug 2015; (). Epub ahead of print

Detection of soluble EpCAM (sEpCAM) in malignant ascites predicts poor overall survival in patients treated with catumaxomab

Seeber A, Braicu I, Untergasser G, Nassir M, Fong D, Botta L, Gastl G, Fiegl H, Zeimet A, Sehouli J, Spizzo G.

Oncotarget 10 Jul 2015; (). Epub ahead of print

BIRC5/Survivin as a target for glycolysis inhibition in high-stage neuroblastoma

Hagenbuchner J, Kiechl-Kohlendorfer U, Obexer P, Ausserlechner MJ

Oncogene 6 Jul 2015; (). [Epub ahead of print]

Multicenter Phase II Study Evaluating Two Cycles of Docetaxel, Cisplatin and Cetuximab as Induction Regimen Prior to Surgery in Chemotherapy-Naive Patients with NSCLC Stage IB-IIIA (INN06-Study

Hilbe W, Pall G, Kocher F, Pircher A, Zabernigg A, Schmid T, Schumacher M, Jamnig H, Fiegl M, Gächter A, Freund M, Kendler D, Manzl C, Zelger B, Popper H, Wöll E

PLoS One 28 Jun 2015; 10(5). eCollection 2015

Soluble EpCAM levels in ascites correlate with positive cytology and neutralize catumaxomab activity in vitro.

Seeber A, Martowicz A, Spizzo G, Buratti T, Obrist P, Fong D, Gastl G, Untergasser G.

BMC Cancer. 7 May 2015; 15(1)372.

Establishment of a human multiple myeloma xenograft model in the chicken to study tumor growth, invasion and angiogenesis.

Agnieszka Martowicz, Johann Kern, Eberhard Gunsilius, Gerold Untergasser.

J Vis Exp. 1 May 2015; ().

Qualitative and quantitative analyses of secondary metabolites in aerial and subaerial of Scorzonera hispanica L. (black salsify)

Granica S, Lohwasser U, Jöhrer K, Zidorn C

Food Chem 15 Apr 2015; (173)321-31.

Marine compounds inhibit growth of multiple myeloma in vitro and in vivo

Normann Steiner, Domenico Ribatti, Wolfgang Willenbacher, Karin Jöhrer, Johann Kern, Christian Marinaccio, Miguel Aracil, Luis F. García-Fernández, Guenther Gastl, Gerold Untergasser, and Eberhard Gunsilius

Oncotarget 10 Apr 2015; 6(10)8200-9.

Modulation of Immune Cell Functions by the E3 Ligase Cbl-b

Lutz-Nicoladoni C, Wolf D, Sopper S

Front Oncol 11 Mar 2015; 5(58). eCollection 2015

Increase in antibody-dependent cellular cytotoxicity (ADCC) in a patient with advanced colorectal carcinoma carrying a KRAS mutation under lenalidomide therapy

Gamerith G, Auer T, Amann A, Putzer D, Schenk B, Kircher B, Hilbe W, Zwierzina H, Loeffler-Ragg J

Cancer Biol Ther 1 Mar 2015; 15(3)266-70.

Longitudinal analysis of 2293 NSCLC patients: a comprehensive study from the TYROL registry.

Kocher F, Hilbe W, Seeber A, Pircher A, Schmid T, Greil R, Auberger J, Nevinny-Stickel M, Sterlacci W, Tzankov A, Jamnig H, Kohler K, Zabernigg A, Frötscher J, Oberaigner W, Fiegl M

Lung Cancer 1 Feb 2015; 87(2)193-200.

Creating a unique, multi-stakeholder Paediatric Oncology Platform to improve drug development for children and adolescents with cancer.

Vassal G, Rousseau R, Blanc P, Moreno L, Bode G, Schwoch S, Schrappe M, Skolnik J, Bergman L, Bradley-Garelik MB, Saha V, Pearson A, Zwierzina H

Eur J Cancer 1 Jan 2015; 51(2)218-24.

Characterization of B and plasma cells in blood, bone marrow, and secondary lymphoid organs of rhesus macaques by multicolor flow cytometry

Neumann B, Klippert A, Raue K, Sopper S, Stahl-Hennig C

J Leukoc Biol 1 Jan 2015; 9()19-30.

2014

31 Dec 2014; ().

Cardiovascular Comorbidities and Events in NSCLC: Often Underestimated but Worth Considering.

Kocher F, Fiegl M, Mian M, Hilbe W

Clin Lung Cancer. 30 Dec 2014; ().

Fluorinated Fe(III) salophene complexes: optimization of tumor cell specific activity and utilization of fluorine labeling for in vitro analysis.

Würtenberger I1, Follia V, Lerch F, Cwikla C, Fahrner N, Kalchschmidt C, Flögel B, Kircher B, Gust R.

J Med Chem 29 Dec 2014; 58(2)588-97.

Longitudinal analysis of 2293 NSCLC patients: a comprehensive study from the TYROL registry.

Florian K, Wolfgang H, Andreas S, Andreas P, Thomas S, Richard G, Jutta A, Meinhard NS, William S, Alexandar T, Herbert J, Karin K, August Z, Josef F, Wilhelm O, Michael F

Lung Cancer 18 Dec 2014; 87(2)193-200.

The role of the Janus-faced transcription factor PAX5-JAK2 in acute lymphoblastic leukemia.

Schinnerl D, Fortschegger K, Kauer M, Marchante JR, Kofler R, Den Boer ML, Strehl S.

Blood 1 Dec 2014; 125(8)1282-91.

Non-pegylated liposomal doxorubicin in lymphoma: patterns of toxicity and outcome in a large observational trial.

Wasle I, Gamerith G, Kocher F, Mondello P, Jaeger T, Walder A, Auberger J, Melchardt T, Linkesch W, Fiegl M, Mian M

Ann Hematol 13 Nov 2014; 94(4)593-601.

Akt-dependent enhanced migratory capacity of Th17 cells from children with lupus nephritis.

Kshirsagar S, Riedl M, Billing H, Tönshoff B, Thangavadivel S, Steuber C, Staude H, Wechselberger G, Edelbauer M.

J Immunol 1 Nov 2014; 193(10)4895-903.

Adipocyte-derived players in hematologic tumors: useful novel targets?

Jöhrer K, Ploner C, Thangavadivel S, Wuggenig P, Greil R

Expert Opin Biol Ther. 1 Oct 2014; 15(1)61-77.

Qualitative and quantitative analyses of secondary metabolites in aerial and subaerial of Scorzonera hispanica L. (black salsify).

Granica S, Lohwasser U, Jöhrer K, Zidorn C.

Food Chem 1 Oct 2014; 173()321-31.

Host factors determine differential disease progression after infection with nef-deleted simian immunodeficiency virus

Sopper S, Mätz-Rensing K, Mühl T, Heeney J, Stahl-Hennig C, Sauermann U

J Gen Virol 1 Oct 2014; 95(10)2273-84.

C10ORF10/DEPP, a transcriptional target of FOXO3, regulates ROS-sensitivity in human neuroblastoma.

Salcher S, Hagenbuchner J, Geiger K, Seiter MA, Rainer J, Kofler R, Hermann M, Kiechl-Kohlendorfer U, Ausserlechner MJ, Obexer P.

Mol Cancer. 1 Sep 2014; 13()224.

The side population of ovarian cancer cells defines a heterogeneous compartment exhibiting stem cell characteristics.

Boesch M, Zeimet AG, Reimer D, Schmidt S, Gastl G, Parson W, Spoeck F, Hatina J, Wolf D, Sopper S.

Oncotarget. 30 Aug 2014; 5(16)7027-39.

Identification of molecular sub-networks associated with cell survival in a chronically SIVmac-infected human CD4+ T cell line

He FQ, Sauermann U, Beer C, Winkelmann S, Yu Z, Sopper S, Zeng AP, Wirth M

Virol J 27 Aug 2014; 11(152).

EpCAM is overexpressed in local and metastatic prostate cancer, suppressed by chemotherapy and modulated by MET-associated miRNA-200c/205.

Massoner P, Thomm T, Mack B, Untergasser G, Martowicz A, Bobowski K, Klocker H, Gires O, Puhr M.

Br J Cancer. 26 Aug 2014; 111(5)955-64.

The synthetic glucocorticoids prednisolone and dexamethasone regulate the same genes in acute lymphoblastic leukemia cells

Bindreither D, Ecker S, Gschirr B, Kofler A, Kofler R, Rainer J

BMC Genomics 7 Aug 2014; 15()662.

X-linked inhibitor of apoptosis protein - a critical death resistance regulator and therapeutic target for personalized cancer therapy.

Obexer P, Ausserlechner MJ

Front Oncol 28 Jul 2014; 4()659-71.

Discovery of Sanggenon G as a natural cell-permeable small-molecular weight inhibitor of X-linked inhibitor of apoptosis protein (XIAP).

Seiter MA, Salcher S, Rupp M, Hagenbuchner J, Kiechl-Kohlendorfer U, Mortier J, Wolber G, Rollinger JM, Obexer P, Ausserlechner MJ.

FEBS Open Bio 5 Jul 2014; 4()659-71.

Neoadjuvant chemo-immunotherapy modifies CD4(+)CD25(+) regulatory T cells (Treg) in non-small cell lung cancer (NSCLC) patients

Pircher A, Gamerith G, Amann A, Reinold S, Popper H, Gächter A, Pall G, Wöll E, Jamnig H, Gastl G, Wolf AM, Hilbe W, Wolf D

Lung Cancer 1 Jul 2014; 85(1)81-7.

Development of an innovative 3D cell culture system to study tumour--stroma interactions in non-small cell lung cancer cells

Amann A, Zwierzina M, Gamerith G, Bitsche M, Huber JM, Vogel GF, Blumer M, Koeck S, Pechriggl EJ, Kelm JM, Hilbe W, Zwierzina H

PLoS One 24 May 2014; 9(3).

Development of a multipurpose GATEWAY-based lentiviral tetracycline-regulated conditional RNAi system (GLTR)

Sigl R, Ploner C, Shivalingaiah G, Kofler R, Geley S

PLoS One 19 May 2014; 9(5).

Expression of EpCAMMF and EpCAMMT variants in human carcinomas.

Fong D, Seeber A, Terracciano L, Kasal A, Mazzoleni G, Lehne F, Gastl G, Spizzo G.

J Clin Pathol. 1 May 2014; 67(5)408-14.

2013

31 Dec 2013; ().

Translational profiling in childhood acute lymphoblastic leukemia: no evidence for glucocorticoid regulation of mRNA translation

Aneichyk T, Bindreither D, Mantinger C, Grazio D, Goetsch K, Kofler R, Rainer J

BMC Genomics 1 Dec 2013; 14()844.

BIRC5/Survivin enhances aerobic glycolysis and drug resistance by altered regulation of the mitochondrial fusion/fission machinery

Hagenbuchner J, Kuznetsov AV, Obexer P, Ausserlechner MJ

Oncogene 1 Oct 2013; 32(40)4748-57.

Loss of membranous expression of the intracellular domain of EpCAM is a frequent event and predicts poor survival in patients with pancreatic cancer

Fong D, Moser P, Kasal A, Seeber A, Gastl G, Martowicz A, Wurm M, Mian C, Obrist P, Mazzoleni G, Spizzo G

Histopathology 1 Oct 2013; epub().

The JAK-inhibitor ruxolitinib impairs dendritic cell function in vitro and in vivo

Heine A, Held SA, Daecke SN, Wallner S, Yajnanarayana SP, Kurts C, Wolf D, Brossart P

Blood 1 Aug 2013; 122(7)1192-202.

The p27-Skp2 axis mediates glucocorticoid-induced cell cycle arrest in T-lymphoma cells

Kullmann MK, Grubbauer C, Goetsch K, Jäkel H, Podmirseg SR, Trockenbacher A, Ploner C, Cato AC, Weiss C, Kofler R, Hengst L

Cell Cycle 1 Aug 2013; 12(16)2625-35 .

A novel Mcl1 variant inhibits apoptosis via increased Bim sequestration.

Hagenbuchner J, Kiechl-Kohlendorfer U, Obexer P, Ausserlechner MJ

Oncotarget 1 Aug 2013; 4(8)1241-52.

Therapy-resistant acute lymphoblastic leukemia (ALL) cells inactivate FOXO3 to escape apoptosis induction by TRAIL and Noxa.

Ausserlechner MJ, Salvador C, Deutschmann A, Bodner M, Viola G, Bortolozzi R, Basso G, Hagenbuchner J, Obexer P

Oncotarget 1 Jul 2013; 4(7)995-1007.

Mitochondria and FOXO3: breath or die

Hagenbuchner J, Ausserlechner MJ

Front Physiol. 1 Jun 2013; 4()147.

The role of the e3 ligase cbl-B in murine dendritic cells

Wallner S, Lutz-Nicoladoni C, Tripp CH, Gastl G, Baier G, Penninger JM, Stoitzner P, Wolf D

PLoS One 1 Jun 2013; 8(6).

EpCAM overexpression prolongs proliferative capacity of primary human breast epithelial cells and supports hyperplastic growth

Martowicz A, Rainer J, Lelong J, Spizzo G, Gastl G, Untergasser G.

Mol Cancer. 1 Jun 2013; 12()56.

EpCAM expression varies significantly and is differentially associated with prognosis in the luminal B HER2(+), basal-like, and HER2 intrinsic subtypes of breast cancer.

Soysal SD, Muenst S, Barbie T, Fleming T, Gao F, Spizzo G, Oertli D, Viehl CT, Obermann EC, Gillanders WE.

Br J Cancer 1 Apr 2013; 108(7)1480-7.

Characterisation of Nox4 Inhibitors from Edible Plants.

Kofler PA, Pircher H, von Grafenstein S, Diener T, Höll M, Liedl KR, Siems K, Jansen-Dürr P

Planta Med 1 Mar 2013; 79(3-4)244-52.

PKCα and PKCβ cooperate functionally in CD3-induced de novo IL-2 mRNA transcription.

Christina LN, Nikolaus T, Katarzyna W, Thomas G, Michael L, Gottfried B.

Immunol Lett. 1 Mar 2013; 151(1-2)31-8.

"Bam," a novel glucocorticoid-induced BH3-only transcript from the BCL2L11/Bim locus, does not appear to be translated.

Mansha M, Hussain A, Kofler A, Grubbauer C, Goetsch K, Ploner C, Kofler R.

Leuk Lymphoma. 1 Feb 2013; 54(2)353-8.

2012

31 Dec 2012; ().

Low expression of junctional adhesion molecule A is associated with metastasis and poor survival in pancreatic cancer.

Fong D, Spizzo G, Mitterer M, Seeber A, Steurer M, Gastl G, Brosch I, Moser P.

Ann Surg Oncol 1 Dec 2012; 19(13)4330-6.

Orphan kinases turn eccentric: a new class of cyclin Y-activated, membrane-targeted CDKs.

Mikolcevic P, Rainer J, Geley S

Cell Cycle 15 Oct 2012; 11(20)3758-68.

Phenotype-dependent effects of EpCAM expression on growth and invasion of human breast cancer cell lines.

Martowicz A, Spizzo G, Gastl G, Untergasser G.

BMC Cancer. 1 Oct 2012; 12()501.

Adoptive transfer of siRNA Cblb-silenced CD8+ T lymphocytes augments tumor vaccine efficacy in a B16 melanoma model.

Hinterleitner, R.#, Gruber, T. #, Pfeifhofer-Obermair, C.#, Lutz-Nicoladoni, C. #, Tzankov, A., Schuster, M., Penninger, J.M., Loibner, H., Lametschwandtner, G., Wolf, D. #, and Baier, G. # # These authors contributed equally to this work.

PLoS One 4 Sep 2012; 7(9).

Promyelocytic leukemia zinc finger protein (PLZF) enhances glucocorticoid-induced apoptosis in leukemic cell line NALM6.

Wasim M, Mansha M, Kofler A, Awan AR, Babar ME, Kofler R

Pak J Pharm Sci. 1 Jul 2012; 25(3)617-21.

Antimyeloma activity of the sesquiterpene lactone cnicin: impact on Pim-2 kinase as a novel therapeutic target.

Jöhrer K, Obkircher M, Neureiter D, Parteli J, Zelle-Rieser C, Maizner E, Kern J, Hermann M, Hamacher F, Merkel O, Wacht N, Zidorn C, Scheideler M, Greil R.

Mol Med (Berl). 1 Jun 2012; 90(6)681-93.

Ovarian cancer stem cells

Zeimet AG, Reimer D, Sopper S, Boesch M, Martowicz A, Roessler J, Wiedemair AM, Rumpold H, Untergasser G, Concin N, Hofstetter G, Muller-Holzner E, Fiegl H, Marth C, Wolf D, Pesta M, Hatina J.

Neoplasma. 1 Jun 2012; 59(6)747-55.

DyeCycle Violet used for side population detection is a substrate of P-glycoprotein.

Boesch M, Reimer D, Rumpold H, Zeimet AG, Sopper S, Wolf D.

Cytometry A 1 Jun 2012; 81(6)517-22 .

FOXO3/FKHRL1 is activated by 5-Aza-2-deoxycytidine (5-azadC) and induces silenced Caspase-8 in neuroblastoma.

Geiger, K.*, Hagenbuchner, J.*, Rupp, M., Fiegl, H., Sergi, C., Meister, B., Kiechl-Kohlendorfer, U., Müller, T., Ausserlechner, M.J.and Obexer, P.

1 Apr 2012; ().

Chemokine-dependent B cell-T cell interactions in chronic lymphocytic leukemia and multiple myeloma - targets for therapeutic intervention?

Jöhrer K, Hofbauer SW, Zelle-Rieser C, Greil R, Hartmann TN.

Expert Opin Biol Ther. 1 Apr 2012; 12(4)425-41.

FOXO3-induced reactive oxygen species are regulated by BCL2L11 (Bim) and SESN3.

Hagenbuchner J, Kuznetsov A, Hermann M, Hausott B, Obexer P, Ausserlechner MJ.

J Cell Sci. 20 Feb 2012; 125(5)1191-203.

The human papillomavirus type 16 E7 oncoprotein targets Myc-interacting zinc-finger protein-1

Morandell D, Kaiser A, Herold S, Rostek U, Lechner S, Mitterberger MC, Jansen-Dürr P, Eilers M, Zwerschke W.

Virology 20 Jan 2012; 422(2)242-53.

Reinforcement of Cancer Immunotherapy by Adoptive Transfer of Cbl-b Deficient CTL combined with Dendritic Cell Vaccination

Lutz-Nicoladoni C, Wallner S, Stoizner P, Pircher M, Gruber T, Wolf AM, Gastl G, Penninger J, Baier G, Wolf D

Immunol & Cell Biol 1 Jan 2012; 90(1)130-4.

Research resource: transcriptional response to glucocorticoids in childhood acute lymphoblastic leukemia.

Rainer J, Lelong J, Bindreither D, Mantinger C, Ploner C, Geley S, Kofler R

Mol Endocrinol. 1 Jan 2012; 26(1)178-93.

2011

31 Dec 2011; ().

Detection of human papillomavirus type 18 E7 oncoprotein in cervical smears: a feasibility study.

Ehehalt D, Lener B, Pircher H, Dreier K, Pfister H, Kaufmann AM, Frangini S, Ressler S, Müller-Holzner E, Schmitt M, Höfler D, Rostek U, Kaiser A, Widschwendter A, Zwerschke W, Jansen-Dürr P

J Clin Microbiol 30 Nov 2011; 50(2)246-57.

The leukemia-specific fusion gene ETV6/RUNX1 perturbs distinct key biological functions primarily by gene repression

Fuka G, Kauer M, Kofler R, Haas OA, Panzer-Grümayer R.

PLoS One. 20 Oct 2011; 6(10).

Novel treatment concepts for graft versus host disease (GvHD)

Wolf D, von Lilienfeld-Toal M, Wolf AM, Schleuning M, von Bergwelt-Baildon M, Held SA, Brossart P

Blood 26 Sep 2011; ().

Regulatory T cells reverse insulin resistance and diabetic nephropathy.

Eller K, Kirsch K, Wolf AM, Sopper S, Tagwerker A, Stanzl A, Wolf D, Patsch W, Rosenkranz AR, Eller P.

Diabetes 12 Sep 2011; ().

TGF-beta plays a pivotal role in tumor immunology for surgically resected non-small cell lung cancer.

Sterlacci W, Wolf D, Savic F, Hilbe W, Schmid T, Jamnig H, Fiegl, M Tzankov A.

Human Pathol. 12 Aug 2011; ().

Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats

Theurl I, Schroll A, Sonnweber T, Nairz M, Theurl M, Willenbacher W, Eller K, Wolf D, Seifert M, Sun CC, Babitt JL, Hong CC, Menhall T, Gearing P, Lin HY, Weiss G.

Blood 5 Jul 2011; 118(18)4977-84.

Glucocorticoid-induced alterations in mitochondrial membrane properties and respiration in childhood acute lymphoblastic leukemia.

Eberhart K, Rainer J, Bindreither D, Ritter I, Gnaiger E, Kofler R, Oefner PJ, Renner K.

Biochim Biophys Acta 3 Jun 2011; 1807(6)719-25.

EpCAM expression in primary tumour tissues and metastases: an immunohistochemical analysis.

Spizzo G, Fong D, Wurm M, Ensinger C, Obrist P, Hofer C, Mazzoleni G, Gastl G, Went P.

J Clin Pathol. 1 May 2011; 64(5)415-20.

Establishing a sensitive and specific assay for determination of glucocorticoid bioactivity.

Oppl B, Kofler A, Schwarz S, Rainer J, Kofler R.

Wien Klin Wochenschr 7 Apr 2011; 123(7-8)222-229.

Dose escalation of imatinib in chronic-phase chronic myeloid leukemia patients: is it still reasonable?

Rudzki J, Wolf D.

Expert Rev Hematol. 4 Apr 2011; 4(2)153-9.

ETV6/RUNX1-positive relapses evolve from an ancestral clone and frequently acquire deletions of genes implicated in glucocorticoid signaling.

Kuster L, Grausenburger R, Fuka G, Kaindl U, Krapf G, Inthal A, Mann G, Kauer M, Rainer J, Kofler R, Hall A, Metzler M, Meyer LH, Meyer C, Harbott J, Marschalek R, Strehl S, Haas OA, Panzer-Grümayer R.

Blood 3 Mar 2011; 117(9)2658-67.

Comprehensive proteomic and transcriptomic characterization of hepatic expression signatures affected in p14 liver conditional knockout mice.

Prokudin I, Stasyk T, Rainer J, Bonn GK, Kofler R, Huber LA.

Proteomics. 11 Feb 2011; 11(3)469-80.

Heterologous Prime-Boost Immunizations with a Virosomal and an Alphavirus Replicon Vaccine.

Walczak M, de Mare A, Riezebos-Brilman A, Regts J, Hoogeboom BN, Visser JT, Fiedler M, Jansen-Dürr P, van der Zee AG, Nijman HW, Wilschut J, Daemen T.

Mol Pharm. 7 Feb 2011; 8(1)65-77.

Subcellular localization of the human papillomavirus 16 E7 oncoprotein in CaSki cells and its detection in cervical adenocarcinoma and adenocarcinoma in situ.

Dreier K, Scheiden R, Lener B, Ehehalt D, Pircher H, Müller-Holzner E, Rostek U, Kaiser A, Fiedler M, Ressler S, Lechner S, Widschwendter A, Even J, Capesius C, Jansen-Dürr P, Zwerschke W.

Virology 5 Jan 2011; 409(1)54-68.

Mast cell recruitment via Treg-derived IL-9 is indispensable for Treg-induced immune-suppression

Eller K, Wolf D, Huber JM, Siebenhaar F, Mayer G, McKenzie ANJ, Maurer M, Rosenkranz AR, Wolf AM.

J Immunol 1 Jan 2011; 186(1)83-91.

Current treatment concepts of Philadelphia-negative MPN

Wolf D, Rudzki J, Gastl G.

Curr Cancer Drug Targets 1 Jan 2011; 11(1)44-55.

FOXO transcription factors as potential therapeutic targets in neuroblastoma

Ausserlechner, M. J., J. Hagenbuchner, S. Fuchs, K. Geiger, and P. Obexer.

In H. Shimada [ed.], Neuroblastoma - Present and Future 1 Jan 2011; ()325-348.

p16INK4A - connecting cell cycle control to cell death regulation in human leukemia, pp.

Obexer, P., J. Hagenbuchner, M. Holzner, and M. J. Ausserlechner

In O. Babusikova, S. Dovat, and K. S. Payne [eds.], T-cell Leukemia. 1 Jan 2011; ().

Effects of EpCAM overexpression on human breast cancer cell lines

Gostner JM, Fong D, Wrulich OA, Lehne F, Zitt M, Hermann M, Krobitsch S, Martowicz A, Gastl G, Spizzo G

BMC Cancer 1 Jan 2011; 11()45.

2010

31 Dec 2010; ().

The role of missing killer cell immunoglobulin-like receptor ligands in T cell replete peripheral blood stem cell transplantation from HLA-identical siblings.

Clausen J, Kircher B, Auberger J, Schumacher P, Ulmer H, Hetzenauer G, Wolf D, Gastl G, Nachbaur D

Biol Blood Marrow Transplant. 24 Oct 2010; 16(2)273-80.

First annual report of the Austrian CML registry.

Schmidt S, Wolf D, Thaler J, Burgstaller S, Linkesch W, Petzer A, Fridrik M, Lang A, Agis H, Valent P, Krieger O, Walder A, Korger M, Schlögl E, Sliwa T, Wöll E, Mitterer M, Eisterer W, Pober M, Gastl G;

Wien Klin Wochenschr 11 Oct 2010; 122(19-20)558-66.

The Neuropeptide Catestatin Acts As a Novel Angiogenic Cytokine via a Basic Fibroblast Growth Factor-Dependent Mechanism.

Theurl M, Schgoer W, Albrecht K, Jeschke J, Egger M, Beer AG, Vasiljevic D, Rong S, Wolf AM, Bahlmann FH, Patsch JR, Wolf D, Schratzberger P, Mahata SK, Kirchmair R.

Circ Res. 7 Oct 2010; (). [Epub ahead of print]

Modifying akt signaling in B-cell chronic lymphocytic leukemia cells.

Hofbauer SW, Piñón JD, Brachtl G, Haginger L, Wang W, Jöhrer K, Tinhofer I, Hartmann TN, Greil R.

Cancer Res. 7 Sep 2010; 70(18)7336-44.

Urinary neopterin does not reflect the local antitumor immune milieu in ovarian cancer.

Zeimet AG, Reimer D, Schwentner L, Fuchs D, Wolf D, Fuith LC, Fiegl H, Doppler W, Concin N, Daxenbichler G, Marth C

Cancer Immunol Immunother 18 Aug 2010; 59(12)1813-23.

Low doses of 2-deoxy-glucose sensitize acute lymphoblastic leukemia cells to glucocorticoid-induced apotosis.

Eberhart K, Renner K, Ritter I, Kastenberger M, Singer K, Hellerbrand C, Kreutz M, Kofler R, Oefner PJ

Leukemia 6 Aug 2010; 23()2167- 2170.

High IL-12 p35 and IL-23 p19 mRNA expression is associated with superior outcome in ovarian cancer.

Wolf AM, Rumpold H, Reimer D, Marth C, Zeimet AG, Wolf D.

Gynecol Oncol. 17 Jun 2010; 118(3)244-50.

Expression, regulation and function of phosphofructo-kinase/fructose-biphosphatases (PFKFBs) in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia cells.

Carlet M, Janjetovic K, Rainer J, Schmidt S, Panzer-Grümayer R, Mann G, Prelog M, Meister B, Ploner C, Kofler R.

BMC Cancer 17 Jun 2010; 10()638.

PLZF/ZBTB16, a glucocorticoid response gene in acute lymphoblastic leukemia, interferes with glucocorticoid-induced apoptosis.

Wasim M, Carlet M, Mansha M, Greil R, Ploner C, Trockenbacher A, Rainer J, Kofler R.

J Steroid Biochem Mol Biol. 21 Apr 2010; 120(4-5)218-27.

Comment on "Cutting edge: depletion of Foxp3+ cells leads to induction of autoimmunity by specific ablation of regulatory T cells in genetically targeted mice".

Wolf D, Wolf AM, Tzankov A.

J Immunol 15 Apr 2010; 184(8)4051.

Functional analyses of Src-like adaptor (SLA), a glucocorticoid-regulated gene in acute lymphoblastic leukemia.

Mansha M, Carlet M, Ploner C, Gruber G, Wasim M, Wiegers GJ, Rainer J, Geley S, Kofler R.

Leukemia Research 1 Apr 2010; 34(4)529-34.

Toll-like Receptor-9 expression in breast and ovarian cancer is associated with poorly differentiated tumors.

Berger, R., Fiegl, H., Goebel, G., Obexer, P., Ausserlechner, MJ., Doppler, W., Hauser-Kronberger, C., Reitsamer, R., Egle, D., Reimer, D., Müller-Holzner, E., Jones, A., Widschwendter, M.

Cancer Sci. 1 Apr 2010; 101(4)1059-66.

The anti-apoptotic protein BCL2L1/Bcl-xL is neutralized by pro-apoptotic PMAIP1/Noxa in neuroblastoma, thereby determining bortezomib sensitivity independent of prosurvival MCL1 expression.

Hagenbuchner J, Ausserlechner MJ, Porto V, David R, Meister B, Bodner M, Villunger A, Geiger K, Obexer P.

J Biol Chem. 5 Mar 2010; 285(10)6904-12.

Atorvastatin attenuates murine anti-glomerular basement membrane glomerulonephritis.

Eller P, Eller K, Wolf AM, Reinstadler SJ, Tagwerker A, Patsch JR, Mayer G, Rosenkranz AR.

Kidney Int 1 Mar 2010; 77(5)428-35.

Tim3 is upregulated and protective in nephrotoxic serum nephritis.

Schroll A, Eller K, Huber JM, Theurl IM, Wolf AM, Weiss G, Rosenkranz AR

Am J Pathol 18 Feb 2010; 176(4)1716-24.

High-dose imatinib improves cytogenetic and molecular remissions in patients with pretreated Philadelphia-positive, BCR-ABL-positive chronic phase chronic myeloid leukemia: first results from the randomized CELSG phase III CML 11 "ISTAHIT" study.

Petzer AL, Wolf D, Fong D, Lion T, Dyagil I, Masliak Z, Bogdanovic A, Griskevicius L, Lejniece S, Goranov S, Gercheva L, Stojanovic A, Peytchev D, Tzvetkov N, Griniute R, Oucheva R, Ulmer H, Kwakkelstein M, Rancati F, Gastl G

Haematologica 9 Feb 2010; 95(6)908-13.

CCR7 deficiency exacerbates injury in acute nephritis due to aberrant localization of regulatory T cells.

Eller K, Weber T, Pruenster M, Wolf AM, Mayer G, Rosenkranz AR, Rot A.

J Am Soc Nephrol 1 Jan 2010; 21(1)42-52.

The cell senescence inducing gene product MORF4 is regulated by degradation via the ubiquitin/proteasome pathway

Tominaga K, Tominaga E, Ausserlechner MJ, Pereira-Smith OM.

Exp Cell Res. 1 Jan 2010; 316(1)92-102.

2009

31 Dec 2009; ().

A benefit-risk assessment of imatinib in chronic myeloid leukaemia and gastrointestinal stromal tumours

Wolf D, Rumpold H.

Drug Saf. 2009 1 Dec 2009; 32(11)1001-15.

PKCtheta and Itk functionally interact during primary mouse CD3+ T cell activation.

Thuille N, Lutz-Nicoladoni C, Letschka T, Hermann-Kleiter N, Heit I, Baier G.

Immunology Letters 22 Nov 2009; 126(1-2)54-9.

Gene therapy with the angiogenic cytokine secretoneurin induces therapeutic angiogenesis by a nitric oxide-dependent mechanism.

Schgoer W, Theurl M, Jeschke J, Beer AG, Albrecht K, Gander R, Rong S, Vasiljevic D, Egger M, Wolf AM, Frauscher S, Koller B, Tancevski I, Patsch JR, Schratzberger P, Piza-Katzer H, Ritsch A, Bahlmann FH, Fischer-Colbrie R, Wolf D, Kirchmair R.

Circ Res 9 Nov 2009; 105(10)994. 1002

p16INK4A sensitizes human leukemia cells to FAS- and glucocorticoid-induced apoptosis via induction of BBC3/Puma and repression of MCL1 and BCL2

Obexer P, Hagenbuchner J, Rupp M, Salvador C, Holzner M, Deutsch M, Porto V, Kofler R, Unterkircher T, Ausserlechner MJ.

J Biol Chem. 6 Nov 2009; 284(45)30933-40.

GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib

Kern J, Untergasser G, Zenzmaier C, Sarg B, Gastl G, Gunsilius E, Steurer M

Blood 29 Oct 2009; 114(18)3960-7.

Effects of weight loss induced by bariatric surgery on hepatic adipocytokine expression

Moschen AR, Molnar C, Wolf AM, Weiss H, Graziadei I, Kaser S, Ebenbichler CF, Stadlmann S, Moser PL, Tilg H.

J Hepato 1 Oct 2009; 51(4)765-77.

The sphingosine 1-phosphate receptor agonist FTY720 potently inhibits regulatory T cell proliferation in vitro and in vivo.

Wolf AM, Eller K, Zeiser R, Dürr C, Gerlach UV, Sixt M, Markut L, Gastl G, Rosenkranz AR, Wolf D.

J Immunol 15 Sep 2009; 183(6)3751-60.

The potent protein kinase C-selective inhibitor AEB071 (sotrastaurin) represents a new class of immunosuppressive agents affecting early T-cell activation.

Evenou JP, Wagner J, Zenke G, Brinkmann V, Wagner K, Kovarik J, Welzenbach KA, Weitz-Schmidt G, Guntermann C, Towbin H, Cottens S, Kaminski S, Letschka T, Lutz-Nicoladoni C, Gruber T, Hermann-Kleiter N, Thuille N, Baier G.

Journal of Pharmacological Experimental Therapy 1 Sep 2009; 330(3)792-801.

Anti-leukemic activity of valproic acid and imatinib mesylate on human Ph+ ALL and CML cells in vitro.

Kircher B, Schumacher P, Petzer A, Hoflehner E, Haun M, Wolf AM, Nachbaur D, Gastl G.

Eur J Haematol 1 Jul 2009; 83(1)48-56.

Pyruvate kinase isoenzyme M2 is a glycolytic sensor differentially regulating cell proliferation, cell size and apoptotic cell death dependent on glucose supply.

Spoden GA, Rostek U, Lechner S, Mitterberger M, Mazurek S, Zwerschke W.

Exp Cell Res. 27 Jun 2009; (). [Epub ahead of print]

Repression of the BH3-only molecule PMAIP1/Noxa impairs glucocorticoid sensitivity of acute lymphoblastic leukemia cells

Ploner C, Rainer J, Lobenwein S, Geley S, Kofler R.

Apoptosis 1 Jun 2009; 14(6)821-8.

PKC theta cooperates with PKC alpha in alloimmune responses of T cells in vivo.

Gruber T, Hermann-Kleiter N, Pfeifhofer-Obermair C, Lutz-Nicoladoni C, Thuille N, Letschka T, Barsig J, Baudler M, Li J, Metzler B, Nüsslein-Hildesheim B, Wagner J, Leitges M, Baier G.

Molecular Immunology 1 Jun 2009; 46(10)2071-9.

Intratumoral interferon regulatory factor (IRF)-1 but not IRF-2 is of relevance in predicting patient outcome in ovarian cancer.

Zeimet AG, Reimer D, Wolf D, Fiegl H, Concin N, Wiedemair A, Wolf AM, Rumpold H, Müller-Holzner E, Marth C.

Int J Cancer 15 May 2009; 124(10)2353-60.

Repression of BIRC5/survivin by FOXO3/FKHRL1 sensitizes human neuroblastoma cells to DNA damage-induced apoptosis.

Obexer P, Hagenbuchner J, Unterkircher T, Sachsenmaier N, Seifarth C, Böck G, Porto V, Geiger K, Ausserlechner M.

Mol Biol Cell 1 May 2009; 20(7)2041-8.

Levels of glucocorticoid receptor and its ligand determine sensitivity and kinetics of glucocorticoid-induced leukemia apoptosis.

Gruber G, Carlet M, Türtscher E, Meister B, Irving JA, Ploner C, Kofler R.

Leukemia 1 Apr 2009; 23(4)820-3.

Glucocorticoid-regulated microRNAs and mirtrons in acute lymphoblastic leukaemia

Rainer J, Ploner C, Jesacher S, Ploner A, Eduardoff M, Mansha M, Wasim M, Panzer-Grümayer R, Trajanoski Z, Niederegger H, Kofler R.

Leukemia 1 Apr 2009; 23(4)746-52.

The SUMO-E3 ligase PIAS3 targets pyruvate kinase M2.

Spoden GA, Morandell D, Ehehalt D, Fiedler M, Jansen-Dürr P, Hermann M, Zwerschke W.

J Cell Biochem 10 Feb 2009; 107(2)293-302.

Prognostic significance of 14-3-3sigma expression in oral squamous cell carcinoma (OSCC).

Laimer K, Blassnig N, Spizzo G, Kloss F, Rasse M, Obrist P, Schäfer G, Perathoner A, Margreiter R, Amberger A.

Oral Oncol 1 Feb 2009; 45(2)127-34.

The involvement of the fractalkine receptor in the transmigration of neuroblastoma cells through bone-marrow endothelial cells.

Nevo I, Sagi-Assif O, Meshel T, Ben-Baruch A, Jöhrer K, Greil R, Trejo LE, Kharenko O, Feinmesser M, Yron I, Witz IP.

Cancer Lett 8 Jan 2009; 273(1)127-39.

Silencing von Cbl-b, Oncotyrol: neues Konzept der Krebsimmuntherapie

Gruber, T., Lutz-Nicoladoni, C., Hanisch, C

JATROS Hämatologie und Onkologie 1 Jan 2009; 3()50-51.

2008

31 Dec 2008; ().

Tumour-immune cell interactions modulated by chemokines.

Jöhrer K, Pleyer L, Olivier A, Maizner E, Zelle-Rieser C, Greil R.

Expert Opin Biol Ther. 22 Dec 2008; 8(3)269-90.

PKC-theta selectively controls the adhesion-stimulating molecule Rap1.

Letschka T, Kollmann V, Pfeifhofer-Obermair C, Lutz-Nicoladoni C, Obermair GJ, Fresser F, Leitges M, Hermann-Kleiter N, Kaminski S, Baier G.

Blood 1 Dec 2008; 112(12)4617-27.

High expression of TROP2 correlates with poor prognosis in pancreatic cancer.

Fong D, Moser P, Krammel C, Gostner JM, Margreiter R, Mitterer M, Gastl G, Spizzo G.

Br J Cancer 21 Oct 2008; 99(8)1290-5.

Human papillomavirus type 45 E7 is a transforming protein inducing retinoblastoma protein degradation and anchorage-independent cell cycle progression.

Morandell, D., Rostek, U., Bouvard, V., Campo-Fernández, B., Fiedler, M. Jansen-Dürr, P., and W. Zwerschke.

Virology 15 Sep 2008; 379(1)20-9.

The nuclear orphan receptor NR2F6 suppresses lymphocyte activation and T helper 17-dependent autoimmunity.

Hermann-Kleiter N, Gruber T, Lutz-Nicoladoni C, Thuille N, Fresser F, Labi V, Schiefermeier N, Warnecke M, Huber L, Villunger A, Eichele G, Kaminski S, Baier G.

Immunity 15 Aug 2008; 29(2)205-16.

Premature senescence of human endothelial cells induced by inhibition of glutaminase.

Unterluggauer H, Mazurek S, Lener B, Hütter E, Eigenbrodt E, Zwerschke W, Jansen-Dürr P.

Biogerontology 1 Aug 2008; 9(4)247-59. Epub 2008 Mar 4

Myocardial ischaemia-reperfusion injury in haematopoietic cell-restricted beta1 integrin knockout mice.

Metzler B, Haubner B, Conci E, Voelkl J, Jehle J, Bauer M, Wolf D, Pachinger O, Xu Q.

Exp Physiol 1 Jul 2008; 93(7)825-33.

Premature aging of the immune system in children with juvenile idiopathic arthritis.

Prelog M, Schwarzenbrunner N, Sailer-Höck M, Kern H, Klein-Franke A, Ausserlechner MJ, Koppelstaetter C, Brunner A, Duftner C, Dejaco C, Strasak AM, Müller T, Zimmerhackl LB, Brunner J.

Arthritis Rheum. 1 Jul 2008; 58(7)2153-62.

Insulin-like growth factor-induced signals activate mitochondrial respiration.

Unterluggauer H, Hütter E, Viertler HP, Jansen-Dürr P.

Biotechnol J 1 Jun 2008; 3(6)813-6. Journal not listed

Mesenchymal stem cells as cellular immunosuppressants.

Wolf D, Wolf AM.

Lancet 10 May 2008; 371(9624)1553-4.

Differential effects of rapamycin in anti-GBM glomerulonephritis.

Hochegger K, Jansky GL, Soleiman A, Wolf AM, Tagwerker A, Seger C, Griesmacher A, Mayer G, Rosenkranz AR.

J Am Soc Nephrol 1 May 2008; 19(8)1520-9.

Isotype-specific inhibitors of the glycolytic key regulator pyruvate kinase subtype M2 moderately decelerate tumor cell proliferation.

Spoden GA, Mazurek S, Morandell D, Bacher N, Ausserlechner MJ, Jansen-Dürr P, Eigenbrodt E, Zwerschke W.

Int J Cancer 18 Apr 2008; 123(2)312-321. [Epub ahead of print]

Endothelial cells from cord blood CD133(+)CD34(+) progenitors share phenotypic, functional and gene expression profile similarities with lymphatics.

Nguyen VA, Fürhapter C, Obexer P, Stössel H, Romani N, Sepp N.

J Cell Mol Med. 9 Apr 2008; (). [Epub ahead of print]Click here to read

The Dickkopf-homolog 3 is expressed in tumor endothelial cells and supports capillary formation.

Untergasser G, Steurer M, Zimmermann M, Hermann M, Kern J, Amberger A, Gastl G, Gunsilius E.

Int J Cancer. 1 Apr 2008; 122(7)1539-47.

The effect of secretory leukocyte protease inhibitor (SLPI) on ischemia/reperfusion injury in cardiac transplantation.

Schneeberger S, Hautz T, Wahl SM, Brandacher G, Sucher R, Steinmassl O, Steinmassl P, Wright CD, Obrist P, Werner ER, Mark W, Troppmair J, Margreiter R, Amberger A.

Am J Transplant. 1 Apr 2008; 8(4)773-82.

Possible role for gene expression profiling in predicting responses to conventional or targeted drugs in patients with chronic myeloid leukemia.

Schmidt S, Gastl G, Wolf D.

Leuk Lymphoma 1 Apr 2008; 49(4)643-7.

Autocrine formation of hepcidin induces iron retention in human monocytes.

Theurl I, Theurl M, Seifert M, Mair S, Nairz M, Rumpold H, Zoller H, Bellmann-Weiler R, Niederegger H, Talasz H, Weiss G.

Blood 15 Feb 2008; 111(4)2392-9.

The BCL2 rheostat in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia.

Ploner C, Rainer J, Niederegger H, Eduardoff M, Villunger A, Geley S, Kofler R.

Epub 2007 Nov 29. 1 Feb 2008; 22(2)7-370.

Dickkopf-3 as a new potential marker for neoangiogenesis in colorectal cancer: expression in cancer tissue and adjacent non-cancerous tissue.

Zitt M, Untergasser G, Amberger A, Moser P, Stadlmann S, Zitt M, Müller HM, Mühlmann G, Perathoner A, Margreiter R, Gunsilius E and Öfner D.

Dis Markers 1 Feb 2008; 24(2)101-9.

TROP2: a novel prognostic marker in squamous cell carcinoma of the oral cavity.

Fong D, Spizzo G, Gostner JM, Gastl G, Moser P, Krammel C, Gerhard S, Rasse M, Laimer K.

Mod Pathol. 1 Feb 2008; 21(2)186-91.

SFRP2 methylation in fecal DNA-a marker for colorectal polyps.

Oberwalder M, Zitt M, Wöntner C, Fiegl H, Goebel G, Zitt M, Köhle O, Mühlmann G, Amberger A, Öfner D, Margreiter R and Müller HM.

Int J Colorectal Dis 1 Jan 2008; 23(1)15-9.

EpCAM expression in squamous cell carcinoma of the oral cavity: frequency and relationship to clinicopathologic features.

Laimer K, Fong D, Gastl G, Obrist P, Kloss F, Tuli T, Gassner R, Rasse M, Norer B, Spizzo G.

Oral Oncol 1 Jan 2008; 44(1)72-7.

Quantification of circulating endothelial and progenitor cells: comparison of quantitative PCR and four-channel flow cytometry.

Steurer M, Kern J, Zitt M, Amberger A, Bauer M, Gastl G, Untergasser G, Gunsilius E.

BMC Res Notes 1 Jan 2008; 28(1)71.

2007

31 Dec 2007; ().

Human papillomavirus type 16 E7 oncoprotein inhibits apoptosis mediated by nuclear insulin-like growth factor-binding protein-3 by enhancing its ubiquitin/proteasome-dependent degradation.

Santer FR, Moser B, Spoden GA, Jansen-Dürr P, Zwerschke W.

Carcinogenesis 1 Dec 2007; 28()2511-20.

High-risk human papillomavirus E7 oncoprotein detection in cervical squamous cell carcinoma.

Ressler S, Scheiden R, Dreier K, Laich A, Müller-Holzner E, Pircher H, Morandell D, Stein I, Viertler HP, Santer FR, Widschwendter A, Even J, Jansen-Dürr P, Capesius C, Zwerschke W.

Clin Cancer Res 1 Dec 2007; 13()7067-72.

Bilirubin inhibits tumor cell growth via activation of ERK.

Ollinger R, Kogler P, Troppmair J, Hermann M, Wurm M, Drasche A, Königsrainer I, Amberger A, Weiss H, Ofner D, Bach FH, Margreiter R.

Cell Cycle 1 Dec 2007; 6(24)3078-85.

STAT1 activation in squamous cell cancer of the oral cavity: a potential predictive marker of response to adjuvant chemotherapy.

Laimer K, Spizzo G, Obrist P, Gastl G, Brunhuber T, Schäfer G, Norer B, Rasse M, Haffner MC, Doppler W.

Cancer 15 Jul 2007; 110(2)326-33.

Lipocalin-2 regulates the inflammatory response during ischemia and reperfusion of the transplanted heart

Aigner F, Maier HT, Schwelberger HG, Wallnöfer EA, Amberger A, Obrist P, Berger T, Mak TW, Maglione M, Margreiter R, Schneeberger S, Troppmair J.

Am J Transplant 1 Apr 2007; 7(4)779-88.

FKHRL1- mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells.

Obexer P, Geiger K, Ambros PF, Meister B, Ausserlechner MJ.

Cell Death Differ. 1 Mar 2007; 14(3)534-47.

Methylation status of the Ep-CAM promoter region in human breast cancer cell lines and breast cancer tissue.

Spizzo G, Gastl G, Obrist P, Fong D, Haun M, Grunewald K, Parson W, Eichmann C, Millinger S, Fiegl H, Margreiter R, Amberger A.

Cancer Lett. 8 Feb 2007; 246(1-2)253-61. Epub 2006 Apr 18.

High EGFR expression predicts poor prognosis in patients with squamous cell carcinoma of the oral cavity and oropharynx: a TMA-based immunohistochemical analysis.

Laimer K, Spizzo G, Gastl G, Obrist P, Brunhuber T, Fong D, Barbieri V, Jank S, Doppler W, Rasse M, Norer B.

Oral Oncol. 1 Feb 2007; 43(2)193-8. Epub 2006 Jul 18.

Identification, tissue expression, and glucocorticoid responsiveness of alternative first exons of the human glucocorticoid receptor.

Presul E, Schmidt S, Kofler R, Helmberg A.

J Mol Endocrinol. 1 Feb 2007; 38(1-2)79-90.

DNA methylation in colorectal cancer – impact on screening and therapy monitoring modalities?

Zitt M, Zitt M, Muller HM.

Dis markers 1 Jan 2007; 23(1-2)51-71.

High-risk HPV E7 oncoprotein expression in cervical squamous cell carcinoma.

Ressler, S., Scheiden, R., Dreier, K., Laich, A., Müller-Holzner, E., Pircher, H., Morandell, D., Stein, I., Viertler, H.P., Santer, F.R., Widschwendter, A., Even, J., Jansen-Dürr, P., Capesius, C. and W. Zwerschke

Clin Can Res. 1 Jan 2007; (13)7067-7072.

The human papillomavirus type 16 E7 oncoprotein inhibits apoptosis induced by nuclear insulin-like growth factor binding protein-3 by inducing its ubiquitin/proteasome-dependent degradation.

Santer, F., Moser, B., Spoden, G.A., Jansen-Dürr, P., and W. Zwerschke.

Carcinogenesis 1 Jan 2007; 28()2511-2520.

DNA methylation in colorectal cancer - Impact on screening and therapy monitoring modalities?

Zitt M, Zitt M, Muller HM.

Dis Markers. 1 Jan 2007; 23(1-2)51-71.

Identification of the FHL2 transcriptional coactivator as a new functional target of the E7 oncoprotein of human papillomavirus type 16.

Campo-Fernandez B, Morandell D, Santer FR, Zwerschke W, Jansen-Durr P.

J Virol. 1 Jan 2007; 81(2)1027-32. Epub 2006 Nov 8.

2006

31 Dec 2006; ().

Glucocorticoid resistance in two key models of acute lymphoblastic leukemia occurs at the level of the glucocorticoid receptor.

Schmidt S, Irving JA, Minto L, Matheson E, Nicholson L, Ploner A, Parson W, Kofler A, Amort M, Erdel M, Hall A, Kofler R.

FASEB J. 1 Dec 2006; 20(14)2600-2. Epub 2006 Oct 31.

Overexpression of epithelial cell adhesion molecule (Ep-CAM) is an independent prognostic marker for reduced survival of patients with epithelial ovarian cancer.

Spizzo G, Went P, Dirnhofer S, Obrist P, Moch H, Baeuerle PA, Mueller-Holzner E, Marth C, Gastl G, Zeimet AG.

Gynecol Oncol. 1 Nov 2006; 103(2)483-8. Epub 2006 May 6.

Disseminated tumor cells in peripheral blood: a novel marker for therapy response in locally advanced rectal cancer patients undergoing preoperative chemoradiation.

Zitt M, Zitt M, Muller HM, Dinnewitzer AJ, Schwendinger V, Goebel G, De Vries A, Amberger A, Weiss H, Margreiter R, Ofner D, Oberwalder M.

Dis Colon Rectum. 1 Oct 2006; 49(10)14784-91.

Antitumoral activity of interferon-gamma involved in impaired immune function in cancer patients.

Brandacher G, Winkler C, Schroecksnadel K, Margreiter R, Fuchs D.

Curr Drug Metab. 1 Aug 2006; 7(6)599-612. Review

A retroviral expression system based on tetracycline-regulated tricistronic transactivator/repressor vectors for functional analyses of antiproliferative and toxic genes.

Ausserlechner MJ, Obexer P, Deutschmann A, Geiger K, Kofler R.

Mol Cancer Ther. 1 Aug 2006; 5(8)1927-34.

CARMAweb: comprehensive R- and bioconductor-based web service for microarray data analysis.

Rainer J, Sanchez-Cabo F, Stocker G, Sturn A, Trajanoski Z.

Nucleic Acids Res. 1 Jul 2006; 34(Web Server)498-503.

Ep-CAM expression in pancreatic and ampullary carcinomas: frequency and prognostic relevance.

Fong D, Steurer M, Obrist P, Barbieri V, Margreiter R, Amberger A, Laimer K, Gastl G, Tzankov A, Spizzo G

J Clin Pathol. 14 Jun 2006; ().

Purification and characterisation of the E7 oncoproteins of the high-risk human papillomavirus types 16 and 18.

Fiedler M, Campo-Fernandez B, Laich A, Moser B, Stockl P, Jansen-Durr P, Zwerschke W.

J Virol Methods. 1 Jun 2006; 134(1-2)30-5. Epub 2005 Dec 27.

Suppression of KCMF1 by constitutive high CD99 expression is involved in the migratory ability of Ewing's sarcoma cells.

Kreppel M, Aryee DN, Schaefer KL, Amann G, Kofler R, Poremba C, Kovar H.

Oncogene. 4 May 2006; 25(19)2795-800.

A role of TRAIL in killing osteoblasts by myeloma cells.

Tinhofer I, Biedermann R, Krismer M, Crazzolara R, Greil R.

FASEB J. 1 Apr 2006; 20(6)759-61. Epub 2006 Jan 25.

Nuclear insulin-like growth factor binding protein-3 induces apoptosis and is targeted to ubiquitin/proteasome-dependent proteolysis.

Santer FR, Bacher N, Moser B, Morandell D, Ressler S, Firth SM, Spoden GA, Sergi C, Baxter RC, Jansen-Durr P, Zwerschke W.

Cancer Res. 15 Mar 2006; 66(6)3024-33.

Oxindole alkaloids from Uncaria tomentosa induce apoptosis in proliferating, G0/G1-arrested and bcl-2-expressing acute lymphoblastic leukaemia cells.

Bacher N, Tiefenthaler M, Sturm S, Stuppner H, Ausserlechner MJ, Kofler R, Konwalinka G.

Br J Haematol. 1 Mar 2006; 132(5)615-22.

Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer: effect on tumor-infiltrating T cells.

Brandacher G, Perathoner A, Ladurner R, Schneeberger S, Obrist P, Winkler C, Werner ER, Werner-Felmayer G, Weiss HG, Gobel G, Margreiter R, Konigsrainer A, Fuchs D, Amberger A.

Clin Cancer Res. 15 Feb 2006; 12(4)1144-51.

The cytotoxic activity of the bacteriophage lambda-holin protein reduces tumour growth rates in mammary cancer cell xenograft models.

Agu CA, Klein R, Schwab S, König-Schuster M, Kodajova P, Ausserlechner M, Binishofer B, Bläsi U, Salmons B, Günzburg WH, Hohenadl C.

J Gene Med. 1 Feb 2006; 8(2)229-41.

IL-4 inhibits the TNF-alpha induced proliferation of renal cell carcinoma (RCC) and cooperates with TNF-alpha to induce apoptotic and cytokine responses by RCC: implications for antitumor immune responses.

Falkensammer C, Johrer K, Gander H, Ramoner R, Putz T, Rahm A, Greil R, Bartsch G, Thurnher M.

Cancer Immunol Immunother. 28 Jan 2006; 28-1-2006()1-10.

Disseminated tumor cells in peripheral blood: a novel marker for therapy response in locally advanced rectal cancer patients undergoing preoperative chemoradiation

Zitt M, Zitt M, Muller HM, Dinnewitzer AJ, Schwendinger V, Goebel G, De Vries A, Amberger A, Weiss H, Margreiter R, Ofner D, Oberwalder M.

Dis Colon Rectum 1 Jan 2006; 49(1)1484-91.

Response of human peritoneal mesothelial cells to inflammatory injury is regulated by interleukin-1beta and tumor necrosis factor-alpha.

Stadlmann S, Pollheimer J, Renner K, Zeimet AG, Offner FA, Amberger A.

Wound Repair Regen. 1 Jan 2006; 14(2)187-94.

2005

31 Dec 2005; ().

Expression of the high-risk human papillomavirus type 18 and 45 E7 oncoproteins in cervical carcinoma biopsies.

Fiedler M, Ressler S, Campo-Fernandez B, Laich A, Jansen L, Widschwendter A, Viertler HP, Bacher N, Morandell D, Muller-Holzner E, Durst M, Jansen-Durr P, Zwerschke W.

J Gen Virol. 1 Dec 2005; 86(Pt 12)3235-41.

Apoptosis resistance of senescent human fibroblasts is correlated with the absence of nuclear IGFBP-3.

Hampel B, Wagner M, Teis D, Zwerschke W, Huber LA, Jansen-Durr P.

Aging Cell. 1 Dec 2005; 4(6)325-30.

Ovarian carcinoma cells and IL-1beta-activated human peritoneal mesothelial cells are possible sources of vascular endothelial growth factor in inflammatory and malignant peritoneal effusions.

Stadlmann S, Amberger A, Pollheimer J, Gastl G, Offner FA, Margreiter R, Zeimet AG.

Gynecol Oncol. 1 Jun 2005; 97(3)784-9.

G1 arrest by p16INK4A uncouples growth from cell cycle progression in leukemia cells with deregulated cyclin E and c-Myc expression.

Ausserlechner MJ, Obexer P, Geley S, Kofler R.

Leukemia. 1 Jun 2005; 19(6)1051-7.

Monocyte-mediated T-cell suppression and augmented monocyte tryptophan catabolism after human hematopoietic stem-cell transplantation.

Hainz U, Obexer P, Winkler C, Sedlmayr P, Takikawa O, Greinix H, Lawitschka A, Potschger U, Fuchs D, Ladisch S, Heitger A.

Blood. 15 May 2005; 105(10)4127-34. Epub 2005 Jan 27

14-3-3sigma expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients.

Perathoner A, Pirkebner D, Brandacher G, Spizzo G, Stadlmann S, Obrist P, Margreiter R, Amberger A.

Clin Cancer Res. 1 May 2005; 11(9)3274-9.

Polyacetylenes from the Apiaceae vegetables carrot, celery, fennel, parsley, and parsnip and their cytotoxic activities.

Zidorn C, Johrer K, Ganzera M, Schubert B, Sigmund EM, Mader J, Greil R, Ellmerer EP, Stuppner H.

J Agric Food Chem. 6 Apr 2005; 53(7)2518-23.

Up-regulation of functional chemokine receptor CCR3 in human renal cell carcinoma.

Johrer K, Zelle-Rieser C, Perathoner A, Moser P, Hager M, Ramoner R, Gander H, Holtl L, Bartsch G, Greil R, Thurnher M.

Clin Cancer Res. 1 Apr 2005; 11(7)2459-65.

Cancer cell line identification by short tandem repeat profiling: power and limitations.

Parson W, Kirchebner R, Muhlmann R, Renner K, Kofler A, Schmidt S, Kofler R.

FASEB J. 1 Mar 2005; 19(3)434-6. Epub 2005 Jan 6.

Glucocorticoid-induced apoptosis and glucocorticoid resistance in acute lymphoblastic leukemia.

Ploner C, Schmidt S, Presul E, Renner K, Schrocksnadel K, Rainer J, Riml S, Kofler R.

J Steroid Biochem Mol Biol. 1 Feb 2005; 93(2-5)153-60. Epub 2005 Jan 26.

Circulating nucleic acids in plasma or serum (CNAPS) as prognostic and predictive markers in patients with solid neoplasias.

Goebel G, Zitt M, Zitt M, Muller HM.

Dis Markers 1 Jan 2005; 21(3)105-20.

Sensitization of colon cancer cell lines to butyrate-mediated proliferation inhibition by combined application of indomethacin and nordihydroguaiaretic acid.

Galfi P, Neogrady Z, Amberger A, Margreiter R, Csordas A.

Cancer Detect Prev. 1 Jan 2005; 29(3)276-85. Epub 2005 Feb 17.

2004

31 Dec 2004; ().

Inhibition by cytoplasmic nucleotides of a new cation channel in freshly isolated human and rat type II pneumocytes.

Mair N, Frick M, Bertocchi C, Haller T, Amberger A, Weiss H, Margreiter R, Streif W, Dietl P.

Am J Physiol Lung Cell Mol Physiol. 1 Dec 2004; 287(6)1284-92.

Is higher income and educational status associated with poorer outcome in patients with Hodgkin's disease?

Holzner B, Fischhofer M, Kemmler G, Kopp M, Sperner-Unterweger B, Krugmann J, Dirnhofer S, Greil R.

Eur J Haematol. 1 Nov 2004; 73(5)318-24.

Glucocorticoid-induced apoptosis and glucocorticoid resistance: molecular mechanisms and clinical relevance.

Schmidt S, Rainer J, Ploner C, Presul E, Riml S, Kofler R.

Cell Death Differ. 1 Jul 2004; 11(Suppl 1)45-55.

Glucocorticoid receptor heterozygosity combined with lack of receptor auto-induction causes glucocorticoid resistance in Jurkat acute lymphoblastic leukemia cells.

Riml S, Schmidt S, Ausserlechner MJ, Geley S, Kofler R.

Cell Death Differ. 1 Jul 2004; 11(Suppl 1)65-72.

Quality of life of patients with chronic lymphocytic leukemia: results of a longitudinal investigation over 1 yr.

Holzner B, Kemmler G, Kopp M, Nguyen-Van-Tam D, Sperner-Unterweger B, Greil R.

Eur J Haematol. 1 Jun 2004; 72(6)381-9.

High level HPV-16 E7 oncoprotein expression correlates with reduced pRb-levels in cervical biopsies.

Fiedler M, Muller-Holzner E, Viertler HP, Widschwendter A, Laich A, Pfister G, Spoden GA, Jansen-Durr P, Zwerschke W.

FASEB J. 1 Jun 2004; 18(10)1120-2. pub 2004 May 20.

Unfavourable prognosis of patients with trisomy 18q21 detected by fluorescence in situ hybridisation in t(11;18) negative, surgically resected, gastrointestinal B cell lymphomas.

Krugmann J, Tzankov A, Dirnhofer S, Fend F, Greil R, Siebert R, Erdel M.

J Clin Pathol. 1 Apr 2004; 57(4)360-4.

Aberrant tetranectin expression in human breast carcinomas as a predictor of survival.

Obrist P, Spizzo G, Ensinger C, Fong D, Brunhuber T, Schafer G, Varga M, Margreiter R, Amberger A, Gastl G, Christiansen M.

J Clin Pathol. 1 Apr 2004; 57(4)417-21.

Transendothelial migration of myeloma cells is increased by tumor necrosis factor (TNF)-alpha via TNF receptor 2 and autocrine up-regulation of MCP-1.

Johrer K, Janke K, Krugmann J, Fiegl M, Greil R.

Clin Cancer Res. 15 Mar 2004; 10(6)1901-10.

Reduction of intracellular pH inhibits constitutive expression of cyclooxygenase-2 in human colon cancer cells.

Pirkebner D, Fuetsch M, Wittmann W, Weiss H, Haller T, Schramek H, Margreiter R, Amberger A.

J Cell Physiol. 1 Feb 2004; 198(2)295-301.

Cyclin D3 and c-MYC control glucocorticoid-induced cell cycle arrest but not apoptosis in lymphoblastic leukemia cells.

Ausserlechner MJ, Obexer P, Bock G, Geley S, Kofler R.

Cell Death Differ. 1 Feb 2004; 11(2)165-74.

2003

31 Dec 2003; ().

Functional analysis of the mutated Epstein-Barr virus oncoprotein LMP1(69del): implications for a new role of naturally occurring LMP1 variants.

Larcher C, Bernhard D, Schaadt E, Adler B, Ausserlechner MJ, Mitterer M, Huemer HP.

Haematologica. 1 Dec 2003; 88(12)1324-35.

A conceptual view on glucocorticoid-lnduced apoptosis, cell cycle arrest and glucocorticoid resistance in lymphoblastic leukemia.

Renner K, Ausserlechner MJ, Kofler R.

Curr Mol Med. 1 Dec 2003; 3(8)707-17.

Metabolic analysis of senescent human fibroblasts reveals a role for AMP in cellular senescence.

Zwerschke W, Mazurek S, Stockl P, Hutter E, Eigenbrodt E, Jansen-Durr P.

Biochem J. 1 Dec 2003; 376(Pt 2)403-11.

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa.

Villunger A, Michalak EM, Coultas L, Müllauer F, Böck G, Ausserlechner MJ, Adams JM, Strasser A.

Science. 7 Nov 2003; 302(5647)1036-8.

Disruption of the integrity of human peritoneal mesothelium by interleukin-1beta and tumor necrosis factor-alpha.

Stadlmann S, Raffeiner R, Amberger A, Margreiter R, Zeimet AG, Abendstein B, Moser PL, Mikuz G, Klosterhalfen B, Offner FA.

Virchows Arch. 1 Nov 2003; 443(5)678-85. Epub 2003 Jul 26.

Cytokine-regulated expression of collagenase-2 (MMP-8) is involved in the progression of ovarian cancer.

Stadlmann S, Pollheimer J, Moser PL, Raggi A, Amberger A, Margreiter R, Offner FA, Mikuz G, Dirnhofer S, Moch H.

Eur J Cancer. 1 Nov 2003; 39(17)2499-505.

Heparanase-1 gene expression in normal, hyperplastic and neoplastic prostatic tissue.

Stadlmann S, Moser PL, Pollheimer J, Steiner P, Krugmann J, Dirnhofer S, Mikuz G, Margreiter R, Amberger A.

Eur J Cancer. 1 Oct 2003; 39(15)2229-33.

Senescence-associated cell death of human endothelial cells: the role of oxidative stress.

Unterluggauer H, Hampel B, Zwerschke W, Jansen-Durr P.

Exp Gerontol. 1 Oct 2003; 38(10)1149-60.

Changes of mitochondrial respiration, mitochondrial content and cell size after induction of apoptosis in leukemia cells.

Renner K, Amberger A, Konwalinka G, Kofler R, Gnaiger E.

Biochim Biophys Acta. 23 Sep 2003; 1642(1-2)115-23.

Tracking death dealing by Fas and TRAIL in lymphatic neoplastic disorders: pathways, targets, and therapeutic tools.

Greil R, Anether G, Johrer K, Tinhofer I.

J Leukoc Biol. 1 Sep 2003; 74(3)311-30.

Resistance to glucocorticoid-induced apoptosis in lymphoblastic leukemia.

Kofler R, Schmidt S, Kofler A, Ausserlechner MJ.

J Endocrinol. 1 Jul 2003; 178(1)19-27.

Tetrocarcin-A--induced ER stress mediates apoptosis in B-CLL cells via a Bcl-2--independent pathway.

Anether G, Tinhofer I, Senfter M, Greil R.

Blood. 1 Jun 2003; 101(11)4561-8. Epub 2003 Jan 30.

Prognostic significance of CD20 expression in classical Hodgkin lymphoma: a clinicopathological study of 119 cases.

Tzankov A, Krugmann J, Fend F, Fischhofer M, Greil R, Dirnhofer S.

Clin Cancer Res. 1 Apr 2003; 9(4)1381-6.

Correlation of COX-2 and Ep-CAM overexpression in human invasive breast cancer and its impact on survival.

Spizzo G, Gastl G, Wolf D, Gunsilius E, Steurer M, Fong D, Amberger A, Margreiter R, Obrist P.

Br J Cancer. 24 Feb 2003; 88(4)574-8.

Tuning the rheostat of the myelopoietic system via Fas and TRAIL.

Greil R, Anether G, Johrer K, Tinhofer I.

Crit Rev Immunol. 1 Jan 2003; 23(4)301-22.

2002

31 Dec 2002; ().

Gene expression profiling of prolonged cold ischemia and reperfusion in murine heart transplants.

Amberger A, Schneeberger S, Hernegger G, Brandacher G, Obrist P, Lackner P, Margreiter R, Mark W.

Transplantation. 27 Nov 2002; 74(10)1441-9.

Stressful death of T-ALL tumor cells after treatment with the anti-tumor agent Tetrocarcin-A.

Tinhofer I, Anether G, Senfter M, Pfaller K, Bernhard D, Hara M, Greil R.

FASEB J. 1 Aug 2002; 16(10)1295-7. Epub 2002 Jun 7.

Regulation and function of the cytokine-inducible SH-2 domain proteins, CIS and SOCS3, in mammary epithelial cells.

Tonko-Geymayer S, Goupille O, Tonko M, Soratroi C, Yoshimura A, Streuli C, Ziemiecki A, Kofler R, Doppler W.

Mol Endocrinol. 1 Jul 2002; 16(7)1680-95.

Defective T-helper cell function after T-cell-depleting therapy affecting naive and memory populations.

Heitger A, Winklehner P, Obexer P, Eder J, Zelle-Rieser C, Kropshofer G, Thurnher M, Holter W.

Blood 1 Jun 2002; 99(11)4053-62.

Suberoylanilide hydroxamic acid (SAHA) overcomes multidrug resistance and induces cell death in P-glycoprotein-expressing cells.

Ruefli AA, Bernhard D, Tainton KM, Kofler R, Smyth MJ, Johnstone RW.

Int J Cancer. 10 May 2002; 99(2)292-8.

Mitochondrial function in glucocorticoid triggered T-ALL cells with transgenic bcl-2 expression.

Renner K, Kofler R, Gnaiger E.

Mol Biol Rep. 1 Jan 2002; 29(1-2)97-101.

Biphasic oxygen kinetics of cellular respiration and linear oxygen dependence of antimycin A inhibited oxygen consumption.

Hutter E, Renner K, Jansen-Durr P, Gnaiger E.

Mol Biol Rep. 1 Jan 2002; 29(1-2)83-7.

2001

31 Dec 2001; ().

Metabolic cooperation between different oncogenes during cell transformation: interaction between activated ras and HPV-16 E7.

Mazurek S, Zwerschke W, Jansen-Durr P, Eigenbrodt E.

Oncogene. 18 Oct 2001; 20(47)6891-8.

Inhibition of histone deacetylase activity enhances Fas receptor-mediated apoptosis in leukemic lymphoblasts.

Bernhard D, Skvortsov S, Tinhofer I, Hubl H, Greil R, Csordas A, Kofler R.

Cell Death Differ. 1 Oct 2001; 8(10)1014-21.

The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species.

Ruefli AA, Ausserlechner MJ, Bernhard D, Sutton VR, Tainton KM, Kofler R, Smyth MJ, Johnstone RW.

Proc Natl Acad Sci U S A. 11 Sep 2001; 98(19)10833-8. Epub 2001 Sep 4.

ESMO recommendations for the application of haematopoietic growth factors (hGFs).

Greil, R.

Ann Oncol. 1 Sep 2001; 12(9)1219-20.

Increased lactate production follows loss of mitochondrial membrane potential during apoptosis of human leukaemia cells.

Tiefenthaler M, Amberger A, Bacher N, Hartmann BL, Margreiter R, Kofler R, Konwalinka G.

Br J Haematol. 2001 Sep;114(3):574-80. 1 Sep 2001; 117(3)574-80.

Replicative senescence of human endothelial cells in vitro involves G1 arrest, polyploidization and senescence-associated apoptosis.

Wagner M, Hampel B, Bernhard D, Hala M, Zwerschke W, Jansen-Durr P.

Exp Gerontol. 1 Aug 2001; 36(8)1327-47.

Mitochondrial membrane sensitivity to depolarization in acute myeloblastic leukemia is associated with spontaneous in vitro apoptosis, wild-type TP53, and vicinal thiol/disulfide status.

Pallis M, Grundy M, Turzanski J, Kofler R, Russell N.

Blood. 15 Jul 2001; 98(2)405-13.

Inhibition of store-operated calcium entry contributes to the anti-proliferative effect of non-steroidal anti-inflammatory drugs in human colon cancer cells.

Weiss H, Amberger A, Widschwendter M, Margreiter R, Ofner D, Dietl P.

Int J Cancer. 15 Jun 2001; 92(6)877-80.

The cell cycle inhibitor p16(INK4A) sensitizes lymphoblastic leukemia cells to apoptosis by physiologic glucocorticoid levels.

Ausserlechner MJ, Obexer P, Wiegers GJ, Hartmann BL, Geley S, Kofler R.

J Biol Chem. 15 Jun 2001; 276(24)10984-9.

Resveratrol, a tumor-suppressive compound from grapes, induces apoptosis via a novel mitochondrial pathway controlled by Bcl-2.

Tinhofer I, Bernhard D, Senfter M, Anether G, Loeffler M, Kroemer G, Kofler R, Csordas A, Greil R.

FASEB J. 1 Jun 2001; 15(9)1613-5.

Effects of the human papilloma virus HPV-16 E7 oncoprotein on glycolysis and glutaminolysis: role of pyruvate kinase type M2 and the glycolytic-enzyme complex.

Mazurek S, Zwerschke W, Jansen-Durr P, Eigenbrodt E.

Biochem J. 15 May 2001; 356(Pt 1)247-56.

Gene expression profiles of proliferating vs. G1/G0 arrested human leukemia cells suggest a mechanism for glucocorticoid-induced apoptosis.

Tonko M, Ausserlechner MJ, Bernhard D, Helmberg A, Kofler R.

FASEB J. 1 Mar 2001; 15(3)693-9.

Induction of apoptosis in cervical carcinoma cells by peptide aptamers that bind to the HPV-16 E7 oncoprotein.

Nauenburg S, Zwerschke W, Jansen-Durr P.

FASEB J. 1 Mar 2001; 15(3)592-4. Epub 2001 Jan 19.

Gene expression profiles of proliferating vs. G1/G0 arrested human leukemia cells suggest a mechanism for glucocorticoid-induced apoptosis.

Tonko M, Ausserlechner MJ, Bernhard D, Helmberg A, Kofler R.

FASEB J. 1 Mar 2001; 15(3)93-9.

Interleukin-15 as a potential costimulatory cytokine in CD154 gene therapy of chronic lymphocytic leukemia.

Anether G, Marschitz I, Tinhofer I, Greil R.

Blood. 15 Jan 2001; 99(2)722-3.

Interaction of HSV-1 infected peripheral blood mononuclear cells with cultured dermal microvascular endothelial cells: a potential model for the pathogenesis of HSV-1 induced erythema multiforme.

Larcher C, Gasser A, Hattmannstorfer R, Obexer P, Fürhapter C, Fritsch P, Sepp N.

J Invest Dermatol. 1 Jan 2001; 116(1)150-6.

2000

31 Dec 2000; ().

Human papillomavirus type 16 E7 oncoprotein binds and inactivates growth-inhibitory insulin-like growth factor binding protein 3

Mannhardt B, Weinzimer SA, Wagner M, Fiedler M, Cohen P, Jansen-Durr P, Zwerschke W.

Mol Cell Biol. 1 Sep 2000; 20(17)6483-95.

The molecular basis of glucocorticoid-induced apoptosis of lymphoblastic leukemia cells.

Kofler R.

Histochem Cell Biol. 1 May 2000; 114(1)1-7. Review

Peptide aptamers as isotype-specific inhibitors of the metabolic keyregulator pyruvate kinase subtype M2.

Spoden, G. A., Mazurek, S., Morandell, D., Bacher, N., Ausserlechner, M., Jansen-Dürr, P., Eigenbrodt E., and W. Zwerschke.

Int J Cancer. In press. ; ().

Insulin-like Growth Factor-binding Protein-3 in Osteosarcomas and Normal Bone Tissues.

Ressler S, Radhi J, Aigner T, Loo C, Zwerschke W, Sergi C.

Anticancer Res. ; 29(7)2579-87.

Lymphokine: Biologie und Anwendung in der Immuntherapie von Tumoren.

Wolf D, Wolf AM

Wachstumsfaktoren in der Hämato-Onkologie. ; (). Uni-Med Verlag 2010

Management of Myeloproliferative Diseases in Senior Patients

Wolf D, Stauder R

ESMO Handbook of Cancer in the Senior Patient ; (). Informa Healthcare. 2010.

Management of Myelodysplastic Syndromes in Senior Patients

Stauder R, Wolf D

ESMO Handbook of Cancer in the Senior Patient ; (). Informa Healthcare. 2010